The blood-brain barrier: Physiology and strategies for drug delivery.

期刊介绍

The aim of the Journal is to provide a forum for the critical analysis of advanced drug and gene delivery systems and their applications in human and veterinary medicine. The Journal has a broad scope, covering the key issues for effective drug and gene delivery, from administration to site-specific delivery.In general, the Journal publishes review articles in a Theme Issue format. Each Theme Issue provides a comprehensive and critical examination of current and emerging research on the design and development of advanced drug and gene delivery systems and their application to experimental and clinical therapeutics. The goal is to illustrate the pivotal role of a multidisciplinary approach to modern drug delivery, encompassing the application of sound biological and physicochemical principles to the engineering of drug delivery systems to meet the therapeutic need at hand. Importantly the Editorial Team of ADDR asks that the authors effectively window the extensive volume of literature, pick the important contributions and explain their importance, produce a forward looking identification of the challenges facing the field and produce a Conclusions section with expert recommendations to address the issues.Articles review the current status of a specific topic, giving equal emphasis to the identification of major conceptual and technological challenges to successful drug and gene delivery, to an evaluation of triumphs as well as shortcomings in current conceptual and technical approaches, and to a discussion of their possible solution.

该杂志的目的是为先进的药物和基因传递系统及其在人类和兽医学中的应用提供一个批判性分析的论坛。该杂志内容广泛，涵盖了有效药物和基因递送的关键问题，从给药到特定位点递送。一般而言，该杂志以主题期刊的形式发表综述文章。每一期主题期刊都对当前和新兴的先进药物和基因递送系统的设计和开发及其在实验和临床治疗中的应用进行了全面和批判性的审查。目的是阐明多学科方法在现代药物输送中的关键作用，包括合理的生物学和物理化学原理在药物输送系统工程中的应用，以满足当前的治疗需求。重要的是，ADDR的编辑团队要求作者有效地打开大量文献的窗口，挑选重要的贡献并解释它们的重要性，对该领域面临的挑战进行前瞻性的识别，并产生一个结论部分，其中包含专家建议来解决问题。文章回顾了特定主题的当前状态，同样重视确定成功的药物和基因递送所面临的主要概念和技术挑战，评价当前概念和技术方法的成功和不足，并讨论其可能的解决办法。

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JCR分区 WOS分区等级：Q1区

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