Advances in Hematology 投稿经验-刊鹿论文编译

Prevalence of Anemia and Associated Factors among Newly Diagnosed Patients with Solid Malignancy at Tikur Anbessa Specialized Hospital, Radiotherapy Center, Addis Ababa, Ethiopia

Abstract:

Background Anemia is a common finding in cancer, which is caused by many factors. It is a major cause of morbidity in cancer patients, worsens disease status and impairs treatment outcome; however, little is known about the prevalence of anemia and associated factors among cancer patients during diagnosis in developing countries like Ethiopia. In response to this, we have conducted research with the aim of assessing the prevalence of anemia and associated factors among newly diagnosed patients with solid malignancy at Tikur Anbessa Specialized Hospital (TASH), Radiotherapy center, Addis Ababa, Ethiopia. Methods Descriptive cross-sectional study was conducted from April to May 2014. A total of 422 newly diagnosed patients with solid malignancy attending Radiotherapy center, TASH were enrolled to assess anemia prevalence and associated factors. Data were coded, entered and analyzed using SPSS version16. Using logistic regression, chi squares, Odds ratio and 95% confidence intervals were computed to measure strength of association between variables. p-value\u2009<\u20090.05 was taken as statistically significant. Result Out of 422 respondents, 285 (68%) were females and 153 (36%) of respondents fell into 35–49 age group with age range between 18 and 80\u2009years and the median age of 45. Magnitude of solid cancers was gynecologic (28.9%), breast (22.7%), nasopharyngeal carcinoma (NPC) (7.6%), colorectal (7.1%), sarcoma (6.9%), head and neck (4.5%), thyroid (3.3%), hepatoma (1.9%), and others (17.1%). The overall prevalence of anemia across different tumor was 23% and higher anemia prevalence was noted in gynecologic (37.7%) and colorectal carcinomas (26.7%). The majority of the anemic patients (68%) remained untreated for anemia. The mean trigger hemoglobin for transfusion was 7.7\u2009g/dl. About 83.5% of anemia was mild to moderate type. Performance status (AOR\u2009=\u20093.344; 95% CI 1.410–7.927) and bleeding history (AOR\u2009=\u20093.628; 95% CI 1.800–7.314) showed statistically significant association with occurrence of anemia with p-value\u2009<\u20090.05. Conclusion Among solid cancers, gynecologic cancer remained the dominant one. Anemia prevalence was 23% in general, in which gynecologic and colorectal cancers were more prevalent. ECOG performance status and bleeding history showed a statistically significant association with the occurrence of anemia.

Author Listing： Edosa Kifle;Mintewab Hussein;Jemal Alemu;Wondemagegnhu Tigeneh

Volume： 2019

Pages： None

DOI： 10.1155/2019/8279789

Language： English

Journal： Advances in Hematology

Advances in Hematology

影响因子：0.0

是否综述期刊：否

是否OA：是

是否预警：不在预警名单内

发行时间：-

ISSN：1687-9104

发刊频率：-

收录数据库：Scopus收录/DOAJ开放期刊

出版国家/地区：United Kingdom

出版社：Hindawi

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年发文量	-
国人发稿量	-
国人发文占比	-
自引率	0.0%
平均录取率	-
平均审稿周期	15 Weeks
版面费	-
偏重研究方向	Medicine-Hematology
期刊官网	https://www.hindawi.com/journals/ah
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